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Recombinant Human EphB4/HTK Protein (His Tag) (Active)
Cat. No : CDRP-00022
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Target Information | |
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Target Name | EphB4/HTK |
Synonyms | HTK; MYK1; TYRO11 |
UniProt ID | O00478 |
Accession | NP_004435.3 |
Product Details | |
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Expression Host | HEK293 Cells |
Species | Human |
Tag | C-His |
Molar Mass | 58.5 kDa |
Sequence | Leu 23-Asp 257 |
Application | Functional ELISA |
Background |
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Ephrin type-B receptor 4 is a protein that in humans is encoded by the EPHB4 gene. It is a single-pass type I membrane protein belonging to the ephrin receptor subfamily of protein kinase superfamily. Members of the ephrin and Eph family are local mediators of cell function through largely contact-dependent processes in development and in maturity. Furthermore; EphB4 protein and the corresponding ligand Ephrin-B2 contribute to tumor growth in various human tumors. EphB4 protein has tumor suppressor activities and that regulation of cell proliferation; extracellular matrix remodeling; and invasive potential are important mechanisms of tumor suppression. Therefore; Ephrin-B2/EphB4 may be recognized as a novel prognostic indicator for cancers. |
Properties | |
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Purity | >95% as determined by reducing SDS-PAGE. |
Formulation | Lyophilized from sterile 100 mM Glycine, 10 mM NaCl, 50 mM Tris, pH7.4. |
Reconstitution | Please refer to the printed manual for detailed information. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.