Recombinant Human ECH1 Protein
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Recombinant Human ECH1 Protein

Cat. No : CDRP-00992
size:
Target Information
Target Name ECH1
Synonyms Delta(3; 5)-Delta(2; 4)-dienoyl-CoA isomerase; mitochondrial; ECH1
UniProt ID Q14242
Accession Q13011
Product Details
Expression Host E.coli
Species Human
Tag N-6His
Molar Mass 34.5 kDa
Sequence Ser 26-Phe 131
Background
Human delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase(ECH1) is a member of the hydratase/isomerase superfamily and contains a C-terminal peroxisomal targeting sequence and localizes to peroxisomes. ECH1 shows high sequence similarity to enoyl-CoA hydratases of several species, particularly within a conserved domain characteristic of these proteins. The rat orthologlocalizes to the matrix of both the peroxisome and mitochondria. It can isomerize 3-trans, 5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. ECH1 plays an important role in the auxiliary step of the fatty acid beta-oxidation pathway.
Properties
Purity >97% as determined by reducing SDS-PAGE.
Formulation Supplied as a 0.2 μm filtered solution of 20 mM Tris, 100 mM NaCl, 10% Glycerol, pH8.0.
Reconstitution Please refer to the printed manual for detailed information.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.
Storage Store at < -20 °C, stable for 6 months. Please minimize freeze-thaw cycles.

! For research use only. Not intended for any clinical use.