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Recombinant Human ECH1 Protein
Cat. No : CDRP-00992
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Target Information | |
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Target Name | ECH1 |
Synonyms | Delta(3; 5)-Delta(2; 4)-dienoyl-CoA isomerase; mitochondrial; ECH1 |
UniProt ID | Q14242 |
Accession | Q13011 |
Product Details | |
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Expression Host | E.coli |
Species | Human |
Tag | N-6His |
Molar Mass | 34.5 kDa |
Sequence | Ser 26-Phe 131 |
Background |
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Human delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase(ECH1) is a member of the hydratase/isomerase superfamily and contains a C-terminal peroxisomal targeting sequence and localizes to peroxisomes. ECH1 shows high sequence similarity to enoyl-CoA hydratases of several species, particularly within a conserved domain characteristic of these proteins. The rat orthologlocalizes to the matrix of both the peroxisome and mitochondria. It can isomerize 3-trans, 5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. ECH1 plays an important role in the auxiliary step of the fatty acid beta-oxidation pathway. |
Properties | |
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Purity | >97% as determined by reducing SDS-PAGE. |
Formulation | Supplied as a 0.2 μm filtered solution of 20 mM Tris, 100 mM NaCl, 10% Glycerol, pH8.0. |
Reconstitution | Please refer to the printed manual for detailed information. |
Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. |
Storage | Store at < -20 °C, stable for 6 months. Please minimize freeze-thaw cycles. |
! For research use only. Not intended for any clinical use.