Recombinant Human Cystatin 7/CST7 Protein (Fc Tag) (Active)
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Recombinant Human Cystatin 7/CST7 Protein (Fc Tag) (Active)

Cat. No : CDRP-01391
size:
Target Information
Target Name Cystatin 7/CST7
Synonyms Cystatin-F; Cystatin-7; Cystatin-Like Metastasis-Associated Protein; CMAP; Leukocystatin; CST7
Accession NP_003641.3
Product Details
Expression Host HEK293 Cells
Species Human
Tag C-hFc
Molar Mass 41.3 kDa
Sequence Leu 24-Ser 402
Background
The cystatin superfamily members are important natural cysteine protease inhibitors present in a wide variety of organisms and are divided into three classes. Cystatin F, also known as leukocystatin and CMAP (Cystatin-like Metastasis-Associated Protein), is a type 2 cystatin and its expression is limited to hematopoietic cells, with the highest expression levels being observed in monocytes, dendritic cells, and certain types of T-cells. Furthermore, cystatin F mRNA becomes up-regulated during dendritic cell maturation, and thus suggests a specific role of cystatin F in immune regulation. Cystatin F is produced as a dimer, an inactive cathepsin inhibitor which is activated by chemical reduction. In addition, Cystatin F and its homologues have been observed expressing in various human cancer cell lines established from malignant tumors, and thus indicates a new diagnosis and prevention approach of certain human carcinomas metastasis.
Properties
Purity >95% as determined by reducing SDS-PAGE.
Formulation Lyophilized from sterile 100 mM Glycine, 10 mM NaCl, 50 mM Tris, pH7.5
Reconstitution Please refer to the printed manual for detailed information.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months.

! For research use only. Not intended for any clinical use.