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Recombinant Human CTNNB1 Protein
Cat. No : CDRP-00729
size:
| Target Information | |
|---|---|
| Target Name | CTNNB1 |
| Synonyms | Catenin beta-1; Beta-catenin; CTNNB; OK; SW-cl.35; PRO2286 |
| UniProt ID | P37023 |
| Accession | P35222 |
| Product Details | |
|---|---|
| Expression Host | E.coli |
| Species | Human |
| Tag | N-His |
| Molar Mass | 59 kDa |
| Sequence | Phe 22-Asp 839 |
| Background |
|---|
| Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. |
| Properties | |
|---|---|
| Purity | >95% as determined by reducing SDS-PAGE. |
| Formulation | Lyophilized from sterile PBS, pH7.4. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.