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Recombinant Human CTGF/CCN2 Protein (Fc Tag)
Cat. No : CDRP-00684
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| Target Information | |
|---|---|
| Target Name | CTGF/CCN2 |
| Synonyms | Connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP-8 |
| UniProt ID | P31371 |
| Accession | P29279 |
| Product Details | |
|---|---|
| Expression Host | HEK293 Cells |
| Species | Human |
| Tag | C-Fc |
| Molar Mass | 62.6 kDa |
| Sequence | Leu 29-Tyr 305 |
| Background |
|---|
| CTGF belongs to the CCN (CTGF/Cyr61/Cef10/NOVH) protein family; which is comprised of six secreted proteins that reside in the extracellular matrix (ECM). CTGF causes a variety of cellular responses including reduced cell adhesion and enhanced cell migration and proliferation. CTGF has also been shown to be essential for epithelial to mesenchymal transition (EMT); a process whereby normal functioning cells morph into ones that produce mainly scar tissue (of which collagen in the major protein component). |
| Properties | |
|---|---|
| Purity | >95% as determined by reducing SDS-PAGE. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.