Recombinant Human Collectin-11/COLEC11 Protein (His Tag)
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Recombinant Human Collectin-11/COLEC11 Protein (His Tag)

Cat. No : CDRP-01189
size:
Target Information
Target Name Collectin-11/COLEC11
Synonyms Collectin-11; Collectin Kidney Protein 1; CL-K1; Colec11
UniProt ID Q9H1Y0
Accession Q9BWP8
Product Details
Expression Host HEK293 Cells
Species Human
Tag C-6His
Molar Mass 27.1 kDa
Sequence Cys 2-Phe 377
Background
Collectin-11 is a secreted protein that belongs to the COLEC10/COLEC11 family. Collectin-11 contains one C-type lectin domain and one collagen-like domain. Collectins play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating their recognition and removal. Collectin-11 binds to various sugars including fucose and mannose, but does not bind to glucose, N-acetylglucosamine and N-acetylgalactosamine. It has a higher affinity for fucose compared to mannose. Collectin-11 binds lipopolysaccharides (LPS). It also involved in fundamental development serving as a guidance cue for neural crest cell migration. Defects in Collectin-11 are the cause of 3MC syndrome type 2 (3MC2).
Properties
Purity >90% as determined by reducing SDS-PAGE.
Formulation Lyophilized from a 0.2 μm filtered solution of 20 mM PBS, 150 mM NaCl, pH7.4.
Reconstitution Please refer to the printed manual for detailed information.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months.

! For research use only. Not intended for any clinical use.