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Recombinant Human Carbonic Anhydrase 1/CA1 Protein (His Tag) (Active)
Cat. No : CDRP-00153
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| Target Information | |
|---|---|
| Target Name | Carbonic Anhydrase 1/CA1 |
| Synonyms | Carbonic Anhydrase 1; Carbonate Dehydratase I; Carbonic Anhydrase B; CAB; Carbonic Anhydrase I; CA-I; CA1 |
| UniProt ID | P01303 |
| Accession | P00915 |
| Product Details | |
|---|---|
| Expression Host | E.coli |
| Species | Human |
| Tag | C-6His |
| Molar Mass | 29.9 kDa |
| Sequence | Ser 46-Ile 113 |
| Background |
|---|
| Carbonic Anhydrase 1 (CA1) is a cytosolic enzyme, belonging to the alpha-carbonic anhydrase family. It is highly expressed in erythrocytes and acts as an early marker for erythroid differentiation. Carbonic anhydrase 1 plays a improtant role in many biological processes such as calcification, cellular respiration, bone resorption, acid-base balance. It is activated by imidazole, histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine. At the same time, It is inhibited by sulfonamide derivatives and coumarins. In addition, CA1 is a zinc metalloenzyme that has reversible hydration of carbon dioxide. It can hydrate cyanamide to urea. |
| Properties | |
|---|---|
| Purity | >97% as determined by reducing SDS-PAGE. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 10% Glycerol, pH8.0. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. |
| Storage | Store at < -20 °C, stable for 6 months. Please minimize freeze-thaw cycles. |
! For research use only. Not intended for any clinical use.