Recombinant Human BPI/CAP57 Protein (His Tag)
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Recombinant Human BPI/CAP57 Protein (His Tag)

Cat. No : CDRP-00560
size:
Target Information
Target Name BPI/CAP57
Synonyms Bactericidal permeability-increasing protein; BPI; CAP57
UniProt ID P20109
Accession P17213
Product Details
Expression Host HEK293 Cells
Species Human
Tag C-6His
Molar Mass 52.5 kDa
Sequence Cys 27-Pro 220
Background
Bactericidal permeability-increasing protein(BPI for short), is a secreted protein which belongs to the BPI/LBP/Plunc superfamily, BPI/LBP family. It exists as a monomer or a disulfide-linked homodimer. The cytotoxic action of BPI is limited to many species of Gram-negative bacteria. This specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. BPI has antibacterial activity against the Gram-nagative bacterium P. aeruginosa, and this activity is inhibited by LPS from P. aeruginosa.
Properties
Purity >90% as determined by reducing SDS-PAGE.
Formulation Lyophilized from a 0.2 μm filtered solution of 20 mM PBS, 150 mM NaCl, pH7.4.
Reconstitution Please refer to the printed manual for detailed information.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months.

! For research use only. Not intended for any clinical use.