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Recombinant Human BPGM Protein (His Tag)
Cat. No : CDRP-00353
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Target Information | |
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Target Name | BPGM |
Synonyms | Bisphosphoglycerate Mutase; BPGM; 2; 3-Bisphosphoglycerate Mutase Erythrocyte; 2; 3-Bisphosphoglycerate Synthase; 2; 3-Diphosphoglycerate Mutase; DPGM; BPG-Dependent PGAM; BPGM |
UniProt ID | P08833 |
Accession | P07738 |
Product Details | |
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Expression Host | E.coli |
Species | Human |
Tag | C-6His |
Molar Mass | 31 kDa |
Sequence | Ser 19-Met 93 |
Background |
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Bisphosphoglycerate Mutase (BPGM) is a member of the Phosphoglycerate Mutase family and BPG-Dependent PGAM subfamily. BPGM is a multifunctional enzyme. BPGM catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. It also has phosphoglycerate phosphomutase activity. BPGM plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of 2,3-bisphosphoglycerate (2,3-BPG). Deficiency of BPGM increases the affinity of cells for oxygen and result in hemolytic anemia. |
Properties | |
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Purity | >97% as determined by reducing SDS-PAGE. |
Formulation | Supplied as a 0.2 μm filtered solution of 20 mM Tris, 1 mM DTT, pH8.0. |
Reconstitution | Please refer to the printed manual for detailed information. |
Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. |
Storage | Store at < -20 °C, stable for 6 months. Please minimize freeze-thaw cycles. |
! For research use only. Not intended for any clinical use.