Recombinant Human BPGM Protein (His Tag)
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Recombinant Human BPGM Protein (His Tag)

Cat. No : CDRP-00353
size:
Target Information
Target Name BPGM
Synonyms Bisphosphoglycerate Mutase; BPGM; 2; 3-Bisphosphoglycerate Mutase Erythrocyte; 2; 3-Bisphosphoglycerate Synthase; 2; 3-Diphosphoglycerate Mutase; DPGM; BPG-Dependent PGAM; BPGM
UniProt ID P08833
Accession P07738
Product Details
Expression Host E.coli
Species Human
Tag C-6His
Molar Mass 31 kDa
Sequence Ser 19-Met 93
Background
Bisphosphoglycerate Mutase (BPGM) is a member of the Phosphoglycerate Mutase family and BPG-Dependent PGAM subfamily. BPGM is a multifunctional enzyme. BPGM catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. It also has phosphoglycerate phosphomutase activity. BPGM plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of 2,3-bisphosphoglycerate (2,3-BPG). Deficiency of BPGM increases the affinity of cells for oxygen and result in hemolytic anemia.
Properties
Purity >97% as determined by reducing SDS-PAGE.
Formulation Supplied as a 0.2 μm filtered solution of 20 mM Tris, 1 mM DTT, pH8.0.
Reconstitution Please refer to the printed manual for detailed information.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.
Storage Store at < -20 °C, stable for 6 months. Please minimize freeze-thaw cycles.

! For research use only. Not intended for any clinical use.