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Recombinant Human ApolipoProtein E/ApoE Protein (His Tag)
Cat. No : CDRP-00218
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Target Information | |
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Target Name | ApolipoProtein E/ApoE |
Synonyms | Apolipoprotein E; APOE; Apo-E |
UniProt ID | P02771 |
Accession | P02649 |
Product Details | |
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Expression Host | Human Cells |
Species | Human |
Tag | C-6His |
Molar Mass | 35.3 kDa |
Sequence | Cys 27-Pro 220 |
Background |
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ApoE, a glycoprotein, is a structural component of very low density lipoprotein (vLDL) synthesized by the liver and intestinally synthesized chylomicrons . ApoE is also a constituent of a subclass of high density of lipoproteins (HDL) involved in cholesterol transport . ApoE mediates high affinity binding of chylomicrons and vLDL particles to the LDL receptor, allowing for specific uptake of these particles by the liver, preventing the accumulation of cholesterol rich particles in the plasma . Apolipoprotein E combines with fats (lipids) in the body to form molecules called lipoproteins and Apolipoprotein E is a major component of a specific type of lipoprotein called very low-density lipoproteins (VLDLs). |
Properties | |
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Purity | >90% as determined by reducing SDS-PAGE. |
Formulation | Lyophilized from a 0.2 μm filtered solution of 20 mM PBS, 150 mM NaCl, pH7.4. |
Reconstitution | Please refer to the printed manual for detailed information. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.