Recombinant Human ApolipoProtein A-I/ApoAI Protein (His Tag)
Online Inquiry
* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

Recombinant Human ApolipoProtein A-I/ApoAI Protein (His Tag)

Cat. No : CDRP-00211
size:
Target Information
Target Name ApolipoProtein A-I/ApoAI
Synonyms Apolipoprotein A-I; Apo-AI; ApoA-I; Apolipoprotein A1; APOA1
UniProt ID P02760
Accession P02647
Product Details
Expression Host E.coli
Species Human
Tag N-His
Molar Mass 30.7 kDa
Sequence Met 1-Arg 152
Background
Apolipoprotein A1 (APOA1) is a member of the apolipoprotein family whose members are proteins bind with lipids and form lipoproteins to translate these oil-soluble lipids such as fat and cholesterol through lymphatic and circulatory system. APOA1 is the main component of high density lipoprotein (HDL) in plasma and is involved in the esterification of cholesterol as a cofactor of lecithin-cholesterol acyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters; and thus play a major role in cholesterol efflux from peripheral cells. As a major component of the HDL complex; APOA1 helps to clear cholesterol from arteries. APOA1 is also characterized as a prostacyclin stabilizing factor; and thus may have an anticlotting effect. Defects in encoding gene may result in HDL deficiencies; including Tangier disease; and with systemic non-neuropathic amyloidosis. Men carrying a mutation may develop premature coronary artery disease.
Properties
Purity >95% as determined by reducing SDS-PAGE.
Formulation Lyophilized from sterile PBS, 10% Glycerol, pH7.4.
Reconstitution Please refer to the printed manual for detailed information.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months.

! For research use only. Not intended for any clinical use.