Recombinant Human ApolipoProtein A-I/ApoAI Protein (aa 19-267, His Tag)
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Recombinant Human ApolipoProtein A-I/ApoAI Protein (aa 19-267, His Tag)

Cat. No : CDRP-00210
size:
Target Information
Target Name ApolipoProtein A-I/ApoAI
Synonyms Apolipoprotein A-I; Apo-AI; ApoA-I; Apolipoprotein A1; APOA1
UniProt ID P02751
Accession P02647
Product Details
Expression Host HEK293 Cells
Species Human
Tag C-His
Molar Mass 30 kDa
Sequence Ala 20-Gly 504
Background
Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 plays a critical role in various biological processes; such as Cholesterol metabolism; Lipid metabolism and transport; Steroid metabolism. APOA1 promotes cholesterol efflux from tissues to the liver and thus helps to clear cholesterol from arteries. Defects in this gene resulted in HDL deficiencies; including Tangier disease (TGD); systemic non-neuropathic amyloidosis; premature coronary artery disease; hepatosplenomegaly and progressive muscle wasting and weakness. In addition; ApoA-I is implicated in the anti-endotoxin function of HDL via interaction with lipopolysaccharide or endotoxin.
Properties
Purity >85% as determined by reducing SDS-PAGE.
Formulation Lyophilized from a 0.2 μm filtered solution of 20 mM PBS, 150 mM NaCl, pH7.2.
Reconstitution Please refer to the printed manual for detailed information.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months.

! For research use only. Not intended for any clinical use.