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Recombinant Human Annexin A8/ANXA8 Protein
Cat. No : CDRP-00493
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| Target Information | |
|---|---|
| Target Name | Annexin A8/ANXA8 |
| Synonyms | Annexin A8; Annexin VIII; Annexin-8; Vascular Anticoagulant-Beta; VAC-Beta; ANXA8; ANX8 |
| UniProt ID | P15692-4 |
| Accession | P13928 |
| Product Details | |
|---|---|
| Expression Host | E.coli |
| Species | Human |
| Tag | None |
| Molar Mass | 36.9 kDa |
| Sequence | Arg 29-Glu 227 |
| Background |
|---|
| Annexin A8 (ANXA8) belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Annexin A8 contains 4 annexin repeats separated by linking sequences of variable lengths. A pair of annexin repeats may form one binding site for calcium and phospholipid. ANXA8 is preferentially expressed in acute promyelocytic leukemia (APL) cells, which suggests its participation in hematopoietic cell differentiation. In addition, ANXA8 is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. |
| Properties | |
|---|---|
| Purity | >90% as determined by reducing SDS-PAGE. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20 mM PBS, 150 mM NaCl, pH7.4. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.