Recombinant Human Angiotensinogen/AGT Protein (His Tag)

Cat. No : CDRP-00161

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Target Information
Target Name	Angiotensinogen/AGT
Synonyms	Angiotensinogen; Serpin A8; AGT and SERPINA8; ANHU
UniProt ID	P01375
Accession	P01019

Product Details
Expression Host	HEK293 Cells
Species	Human
Tag	C-6His
Molar Mass	51.7 kDa
Sequence	Ser 112-Thr 270

Background
Angiotensinogen is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Genetic variations in Angiotensinogen are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in the encoding gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

Background

Angiotensinogen is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Genetic variations in Angiotensinogen are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in the encoding gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

Properties
Purity	>97% as determined by reducing SDS-PAGE.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM PBS,150 mM NaCl, pH7.4.
Reconstitution	Please refer to the printed manual for detailed information.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.
Storage	Store at < -20 °C, stable for 6 months. Please minimize freeze-thaw cycles.

! For research use only. Not intended for any clinical use.