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Recombinant Human ALK-1/ACVRL1 Protein (Fc Tag)
Cat. No : CDRP-00762
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Target Information | |
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Target Name | ALK-1/ACVRL1 |
Synonyms | Serine/Threonine-Protein Kinase Receptor R3; SKR3; Activin Receptor-Like Kinase 1; ALK-1; TGF-B Superfamily Receptor Type I; TSR-I; ACVRL1; ACVRLK1; ALK1; HHT; HHT2; ORW2; SKR3 |
UniProt ID | P43303 |
Accession | P37023 |
Product Details | |
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Expression Host | HEK293 Cells |
Species | Human |
Tag | C-Fc |
Molar Mass | 37.6 kDa |
Sequence | Glu 21-Ser 157 |
Background |
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Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-βsuperfamily of ligands. ALK-1 has a high degree of similarity in serine-threonine kinase subdomains, a glycine and serine rich region preceding the kinase-domain, and a C-terminal tail with other activin receptor-like kinase proteins. The mutations of ALK-1 are associated with Rendu-Osler-Weber syndrome 2, this suggests ACVRL1 is associated with blood vessel development and repair. |
Properties | |
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Purity | >90% as determined by reducing SDS-PAGE. |
Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Reconstitution | Please refer to the printed manual for detailed information. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.