Recombinant Human ACE2 Protein (Fc Tag)
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Recombinant Human ACE2 Protein (Fc Tag)

Cat. No : CDRP-01199
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Target Information
Target Name ACE2
Synonyms Angiotensin-Converting Enzyme 2; ACE-Related Carboxypeptidase; Angiotensin-Converting Enzyme Homolog; ACEH; Metalloprotease MPROT15; ACE2
UniProt ID Q9H7M9
Accession Q9BYF1
Product Details
Expression Host HEK293 Cells
Species Human
Tag C-Fc
Molar Mass 110.5 kDa
Sequence Ser 82-Thr 190
Background
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
Properties
Purity >97% as determined by reducing SDS-PAGE.
Formulation Supplied as a 0.2 μM filtered solution of 20 mM Tris-HCl, 300 mM NaCl, 1 mM ZnCl2, 10% Glycerol, pH7.4.
Reconstitution Please refer to the printed manual for detailed information.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.
Storage Store at < -20 °C, stable for 6 months. Please minimize freeze-thaw cycles.

! For research use only. Not intended for any clinical use.