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Recombinant Cynomolgus CD40/TNFRSF5 Protein (His Tag)
Cat. No : CDRP-00009
size:
| Target Information | |
|---|---|
| Target Name | CD40/TNFRSF5 |
| Synonyms | Tumor Necrosis Factor Receptor Superfamily member 5; B-Cell Surface Antigen CD40; Bp50; CD40L Receptor; CDw40; CD40; TNFRSF5 |
| UniProt ID | G7MG20 |
| Accession | G7PG38 |
| Product Details | |
|---|---|
| Expression Host | HEK293 Cells |
| Species | Cynomolgus macaques |
| Tag | C-His |
| Molar Mass | 20.2 kDa |
| Sequence | Glu 108-Leu 261 |
| Background |
|---|
| CD40 is a Type I Transmembrane Glycoprotein that belongs to the TNF Receptor Superfamily. CD40 is expressed in B cells, follicular dendritic cells, dendritic cells, activated monocytes, macrophages, endothelial cells, vascular smooth muscle cells, and several tumor cell lines. The extracellular domain of CD40 is characterized by Cysteine rich repeat regions. Interaction of CD40 with its ligand (CD40L) leads to aggregation of CD40 molecules, which in turn interact with cytoplasmic components to initiate signaling pathways. Several different TRAF proteins (adaptor proteins) have been identified to serves as mediators of the signal transduction. |
| Properties | |
|---|---|
| Purity | >90% as determined by reducing SDS-PAGE. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months. |
! For research use only. Not intended for any clinical use.