(RAC)-Calpain Inhibitor XII

Product Details
Formula	C26H34N4O5
Molecular Weight	482.57
Appearance	Solid
Purity	≥90.0%
Smiles String	O=C(OCC1=CC=CC=C1)NC(C(NC(C(C(NCC2=NC=CC=C2)=O)=O)CCC)=O)CC(C)C

Storage & Handling
Shipping	Room temperature.
Storage	-20 °C, stored under nitrogen *In solvent : -80 °C, 6 months; -20 °C, 1 month (stored under nitrogen)

(Rac)-Calpain Inhibitor XII is a reversible and selective inhibitor of calpain I (μ-calpain, Ki=19 nM). (Rac)-Calpain Inhibitor XII has lower affinities for calpain II (m-calpain, Ki=120 nM) and cathepsin B (Ki=750 nM). (Rac)-Calpain Inhibitor XII has the potential for studying the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury.

! For research use only. Not intended for any clinical use.