RA-2
Cat. No: CDIA-1800
CAS. No.: 1867107-62-7
Size: 50 mg
Product Details |
Formula |
C22H16F2O6 |
Molecular Weight |
414.36 |
Smiles String |
O=C(C1=CC=C(C(F)=C1)O)OCC2=CC=CC(COC(C3=CC=C(C(F)=C3)O)=O)=C2 |
Storage & Handling |
Shipping |
Room temperature. |
Storage |
Please refer to the instruction manual. |
Description
RA-2 is a negative-gating modulator of KCa2/3 channels with an IC50 of 17 nM. RA-2 inhibits bradykinin-induced endothelium-derived hyperpolarization (EDH)-type relaxation in U46619-precontracted rings. RA-2 can help to define the physiologic and pathomechanistic roles of KCa2/3 in the vasculature, central nervous system, and during inflammation.
! For research use only. Not intended for any clinical use.
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