R 80123
Online Inquiry
* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

R 80123

Cat. No: CDIA-2199
CAS. No.: 133718-30-6
Size: 5 mg
Price: Inquiry
Product Details
Formula C26H29N5O3
Molecular Weight 459.54
Appearance Solid
Purity ≥98.0%
Smiles String O=C(N(C1CCCCC1)C)CO/N=C(C2=CC=CC=C2)\C3=CC4=C(N=C(NC(C5)=O)N5C4)C=C3
Storage & Handling
Shipping Room temperature.
Storage Powder -20 °C/3 years, 4 °C/2 years

Description

R 80123 is the Z-isomer of R 79595, is also a highly selective phosphodiesterase inhibitor. The fuction is similar to R 80122 (HY-100615, Revizinone). In vivo: The administration of Revizinone improved the haemodynamic profile with an increase in cardiac output, a decrease in systemic vascular resistance and a stable heart rate and mean arterial blood pressure. With regard to reconstitution of contractility and cardiac function Revizinone (E-isomer) is 10 fold more potent than R 79595 and nearly 100 fold more potent than R 80123 (Z-isomer). Revizinone significantly increases global LV function and systolic wall thickening in ischemic areas at doses greater than or equal to 0.16 mg/kg i.v.

! For research use only. Not intended for any clinical use.