Pyripyropene A
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Pyripyropene A

Cat. No: CDIA-0633
CAS. No.: 147444-03-9
Size: 5 mg
Price: Inquiry
Product Details
Formula C31H37NO10
Molecular Weight 583.63
Appearance Solid
Purity ≥97.0%
Smiles String O=C1OC(C2=CC=CN=C2)=CC3=C1[[email protected]](O)[[email protected]@]4([H])[[email protected]]([[email protected]@H](OC(C)=O)C[[email protected]@]5([H])[[email protected]](C)(COC(C)=O)[[email protected]@H](OC(C)=O)CC[[email protected]@]54C)(C)O3
Storage & Handling
Shipping Room temperature.
Storage Powder -20 °C/3 years

Description

Pyripyropene A is a potent and selective sterol O-acyltransferase 2 (SOAT2)/acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2) inhibitor, with an IC50 of 0.07 µM. Pyripyropene A attenuates hypercholesterolemia and atherosclerosis in vivo.

! For research use only. Not intended for any clinical use.