Propafenone

Product Details
Formula	C21H27NO3
Molecular Weight	341.44
Smiles String	O=C(C1=CC=CC=C1OCC(O)CNCCC)CCC2=CC=CC=C2

Storage & Handling
Shipping	Room temperature.
Storage	Please refer to the instruction manual.

Propafenone (SA-79), a sodium-channel blocker, acts an antiarrhythmic agent. Propafenone also has high affinity for the β receptor (IC50=32 nM). Propafenone blocks the transient outward current (Ito) and the sustained delayed rectifier K current (Isus) with IC50 values of 4.9 μm and 8.6 μm, respectively. Propafenone suppresses esophageal cancer proliferation through inducing mitochondrial dysfunction and induce apoptosis.

! For research use only. Not intended for any clinical use.