Pitavastatin
Cat. No: CDIA-1249
CAS. No.: 147511-69-1
Synonyms: NK-104
Size: 50 mg
Product Details |
Formula |
C25H24FNO4 |
Molecular Weight |
421.46 |
Smiles String |
O=C(O)C[[email protected]](O)C[[email protected]](O)/C=C/C1=C(C2=CC=C(F)C=C2)C3=CC=CC=C3N=C1C4CC4 |
Storage & Handling |
Shipping |
Room temperature. |
Storage |
Please refer to the instruction manual. |
Description
Pitavastatin (NK-104) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects.
! For research use only. Not intended for any clinical use.
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