PF-3882845
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PF-3882845

Cat. No: CDIA-1368
CAS. No.: 1023650-66-9
Size: 50 mg
Price: Inquiry
Product Details
Formula C24H22ClN3O2
Molecular Weight 419.90
Smiles String N#CC1=CC=C(N2N=C(C(C=CC(C(O)=O)=C3)=C3CC4)[[email protected]]4[[email protected]@H]2C5CCCC5)C=C1Cl
Storage & Handling
Shipping Room temperature.
Storage Please refer to the instruction manual.

Description

PF-3882845 is a remarkably high affinity selective and orally efficacious mineralocorticoid receptor (MR binding IC50=2.7 nM) antagonist for hypertension and nephropathy. PF-3882845 also binds to progesterone receptor (PR) with the binding IC50 of 310 nM.

! For research use only. Not intended for any clinical use.