PF-06446846 hydrochloride
Online Inquiry
* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

PF-06446846 hydrochloride

Cat. No: CDIA-0186
CAS. No.: 1632250-50-0
Size: 1 mg
Price: Inquiry
Product Details
Formula C22H21Cl2N7O
Molecular Weight 470.35
Appearance Solid
Purity 99.85%
Smiles String O=C(N(C1=NC=CC=C1Cl)[[email protected]]2CNCCC2)C3=CC=C(N4N=NC5=CC=CN=C54)C=C3.[H]Cl
Storage & Handling
Shipping Room temperature.
Storage 4 °C, sealed storage, away from moisture *In solvent : -80 °C, 6 months; -20 °C, 1 month (sealed storage, away from moisture)

Description

PF-06446846 hydrochloride is an orally active and highly selective inhibitor of translation of Proprotein convertase subtilisin/kexin type 9 (PCSK9). PF-06446846 hydrochloride inhibits PCSK9 by inducing the ribosome to stall around codon 34.

! For research use only. Not intended for any clinical use.