PD146176
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PD146176

Cat. No: CDIA-0328
CAS. No.: 4079-26-9
Synonyms: NSC168807
Size: 1 mg
Price: Inquiry
Product Details
Formula C15H11NS
Molecular Weight 237.32
Appearance Solid
Purity 99.16%
Smiles String C1(N2)=C(CSC3=CC=CC=C31)C4=C2C=CC=C4
Storage & Handling
Shipping Room temperature.
Storage Powder -20 °C/3 years

Description

PD146176 (NSC168807), a 15-Lipoxygenase (15-LO) inhibitor, inhibits rabbit reticulocyte 15-LO (Ki=197 nM, IC50=0.54 μM). PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology by stimulating autophagy in aged triple transgenic mice.

! For research use only. Not intended for any clinical use.