Products

Online Inquiry

* First Name

* Last Name

Phone

* Business Email

Company/Institution

Job Title

* Services or Products of Interest

When do you expect your project to start?

Project Description

* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

PCSK9-IN-11

Cat. No: CDIA-2018

Size: 10 mg

Price: Inquiry

Product Details
Formula	C16H17ClFN5O3
Molecular Weight	381.79
Appearance	Solid
Purity	99.66%
Smiles String	O=C(N1C)N(C)C2=C(N(CC3=CC=CC(Cl)=C3F)C(NCCO)=N2)C1=O

Storage & Handling
Shipping	Room temperature.
Storage	4 °C, protect from light *In solvent : -80 °C, 6 months; -20 °C, 1 month (protect from light)

Description

PCSK9-IN-11 (compound 5r) is a potent and orally active PCSK9 inhibitor. PCSK9-IN-11 exhibits PCSK9 transcriptional inhibitory activity in HepG2 cells, with an IC50 of 5.7 μM. PCSK9-IN-11 increases LDL receptor (LDLR) protein level. PCSK9-IN-11 can be used for atherosclerosis research.

! For research use only. Not intended for any clinical use.