Otamixaban

Product Details
Formula	C25H26N4O4
Molecular Weight	446.50
Appearance	Solid
Purity	98.08%
Smiles String	N=C(C1=CC=CC(C[[email protected]@H](C(OC)=O)[[email protected]](NC(C2=CC=C(C=C2)C3=CC=[N+]([O-])C=C3)=O)C)=C1)N

Storage & Handling
Shipping	Room temperature.
Storage Powder	-20 °C/3 years, 4 °C/2 years

Otamixaban(FXV673) is a potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa. IC50 value: Target: Factor Xa Otamixaban is a potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa. In vivo experiments have demonstrated that Otamixaban is highly efficacious in rodent, canine and porcine models of thrombosis. In addition, recent clinical findings indicate that Otamixaban is efficacious, safe and well tolerated in humans and therefore has considerable potential for the treatment of acute coronary syndrome. This review article chronicles the discovery and pre-clinical data surrounding the fXa inhibitor Otamixaban as well as the recent clinical findings in humans.

! For research use only. Not intended for any clinical use.