Ophiopogonin D
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Ophiopogonin D

Cat. No: CDIA-0387
CAS. No.: 945619-74-9
Size: 1 mg
Price: Inquiry
Product Details
Formula C44H70O16
Molecular Weight 855.02
Appearance Solid
Purity 98.59%
Smiles String C[[email protected]@]12[[email protected]]([[email protected]@H]3C)([H])[[email protected]](O[[email protected]]34CC[[email protected]@H](C)CO4)([H])C[[email protected]@]1([H])[[email protected]@](CC=C5[[email protected]@]6([[email protected]@H](C[[email protected]](O)C5)O[[email protected]@](O[[email protected]](C)[[email protected]](O)[[email protected]@H]7O[[email protected]@](OC[[email protected]@H](O)[[email protected]@H]8O)([H])[[email protected]@H]8O)([H])[[email protected]@H]7O[[email protected]@](O[[email protected]@H](C)[[email protected]](O)[[email protected]]9O)([H])[[email protected]@H]9O)C)([H])[[email protected]]6([H])CC2
Storage & Handling
Shipping Room temperature.
Storage 4 °C, protect from light *In solvent : -80 °C, 6 months; -20 °C, 1 month (protect from light)

Description

Ophiopogonin D, isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C29 steroidal glycoside. Ophiopogonin D is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation, IκBα down-regulation, intracellular Ca2+ overload and activation of pro-inflammatory cytokines by increasing the expression of CYP2J2/EETs and PPARα in human umbilical vein endothelial cells (HUVECs). Ophiopogonin D has been used to treat inflammatory and cardiovascular diseases for thousands of years.

! For research use only. Not intended for any clinical use.