Nepicastat hydrochloride

Cat. No: CDIA-0611

CAS. No.: 170151-24-3

Synonyms: SYN-117 hydrochloride; RS-25560-197 hydrochloride

Size: 5 mg

Price: Inquiry

Product Details
Formula	C14H16ClF2N3S
Molecular Weight	331.81
Appearance	Solid
Purity	98.40%
Smiles String	FC1=CC(F)=C2CC[[email protected]@H](CC2=C1)N3C(CN)=CNC3=S.Cl

Storage & Handling
Shipping	Room temperature.
Storage	4 °C, sealed storage, away from moisture *In solvent : -80 °C, 6 months; -20 °C, 1 month (sealed storage, away from moisture)

Description

Nepicastat hydrochloride (SYN-117 hydrochloride) is a selective, potent, and orally active inhibitor of dopamine-beta-hydroxylase. Nepicastat hydrochloride produces concentration-dependent inhibition of bovine (IC50=8.5 nM) and human (IC50=9 nM) dopamine-beta-hydroxylase. Nepicastat hydrochloride can cross the blood-brain barrier (BBB).

! For research use only. Not intended for any clinical use.