NecroX-7
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NecroX-7

Cat. No: CDIA-1851
CAS. No.: 1120332-55-9
Size: 50 mg
Price: Inquiry
Product Details
Formula C24H29N3O3S
Molecular Weight 439.57
Smiles String O=S1(CCN(CC1)CC2=CC3=C(C(NC4CCOCC4)=C2)NC(C5=CC=CC=C5)=C3)=O
Storage & Handling
Shipping Room temperature.
Storage Please refer to the instruction manual.

Description

NecroX-7 is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen toxicity. NecroX-7 exerts a protective effect by preventing the release of HMGB1 in ischemia/reperfusion injury. NecroX-7 inhibits the HMGB1-induced release of TNF and IL-6, as well as the expression of TLR-4 and receptor for advanced glycation end products. NecroX-7 can be used graft-versus-host disease (GVHD) research.

! For research use only. Not intended for any clinical use.