Nebentan potassium
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Nebentan potassium

Cat. No: CDIA-0835
CAS. No.: 342005-82-7
Synonyms: YM598
Size: 5 mg
Price: Inquiry
Product Details
Formula C24H20KN5O5S
Molecular Weight 529.61
Appearance Solid
Purity 98.30%
Smiles String O=S(/C=C/C1=CC=CC=C1)([N-]C2=NC(C3=NC=CC=N3)=NC(OC)=C2OC4=CC=CC=C4OC)=O.[K+]
Storage & Handling
Shipping Room temperature.
Storage 4 °C, sealed storage, away from moisture *In solvent : -80 °C, 6 months; -20 °C, 1 month (sealed storage, away from moisture)

Description

Nebentan potassium (YM598) is a potent, selective and orally active non-peptide endothelin ETA receptor antagonist through the modification of Bosentan (HY-A0013). Nebentan potassium inhibits [125I] endothelin-1 binding to cloned human endothelin ETA and ETB receptor, with Ki of 0.697 nM and 569 nM, respectively. YM598 can ameliorate the progression of cor pulmonale and myocardial infarction in vivo.

! For research use only. Not intended for any clinical use.