Lomitapide mesylate

Cat. No: CDIA-2357

CAS. No.: 202914-84-9

Synonyms: AEGR-733 mesylate; BMS-201038 mesylate

Size: 50 mg

Price: Inquiry

Product Details
Formula	C40H41F6N3O5S
Molecular Weight	789.83
Smiles String	O=C(C1(CCCCN2CCC(NC(C3=CC=CC=C3C4=CC=C(C(F)(F)F)C=C4)=O)CC2)C5=C(C6=C1C=CC=C6)C=CC=C5)NCC(F)(F)F.O=S(C)(O)=O

Storage & Handling
Shipping	Room temperature.
Storage	Please refer to the instruction manual.

Description

Lomitapide mesylate(AEGR-733; BMS-201038) is an inhibitor of microsomal triglyceride-transfer protein (MTP) wtih in vitro IC50 of 8 nM. IC50 value: 8 nM Target: MTP inhibitor Lomitapide is a small-molecule, microsomal triglyceride transfer protein (MTP) inhibitor, for the treatment of both familial and primary hypercholesterolemia. Oral, once-daily lomitapide will be targeted at patients resistant to HMG-CoA reductase inhibitors (statins) either due to abnormalities in liver function or to discontinuation because of muscle pain.

! For research use only. Not intended for any clinical use.