IMM-H007

Product Details
Formula	C22H23N5O8
Molecular Weight	485.45
Smiles String	CC(O[[email protected]]1[[email protected]@](N2C3=NC=NC(NC4=CC(O)=CC=C4)=C3N=C2)([H])O[[email protected]@H]([[email protected]]1OC(C)=O)COC(C)=O)=O

Storage & Handling
Shipping	Room temperature.
Storage	Please refer to the instruction manual.

IMM-H007 (WS070117) is an orally active and potent AMPK (AMP-activated protein kinase) activator and TGFβ1 (transforming growth factor β1) antagonist. IMM-H007 has protective effects in cardiovascular diseases via activation of AMPK. IMM-H007 negatively regulates endothelium inflammation through inactivating NF-κB and JNK/AP1 signaling. IMM-H007 inhibits ABCA1 degradation. IMM-H007 resolves hepatic steatosis in HFD-fed hamsters by the regulation of lipid metabolism. IMM-H007 can be used for the research of nonalcoholic fatty liver disease (NAFLD) and inflammatory atherosclerosis.

! For research use only. Not intended for any clinical use.