IK1 inhibitor PA-6
Cat. No: CDIA-1065
CAS. No.: 500715-03-7
Synonyms: PA-6
Size: 5 mg
| Product Details |
| Formula |
C31H32N4O2 |
| Molecular Weight |
492.61 |
| Appearance |
Solid |
| Purity |
99.62% |
| Smiles String |
N=C(C1=CC=CC=C1)NC2=CC=C(OCCCCCOC3=CC=C(NC(C4=CC=CC=C4)=N)C=C3)C=C2 |
| Storage & Handling |
| Shipping |
Room temperature. |
| Storage Powder |
-20 °C/3 years, 4 °C/2 years |
Description
IK1 inhibitor PA-6 (PA-6), a pentamidine analogue, is a selective and potent IK1 (KIR2.x ion-channel-carried inward rectifier current) inhibitor, with IC50 values of 12-15 nM for human and mouse KIR2.x currents. IK1 inhibitor PA-6 (PA-6) elevates KIR2.1 protein expression and induces intracellular KIR2.1 accumulation. IK1 inhibitor PA-6 (PA-6) has the potential to treat atrial fibrillation and arrhythmia.
! For research use only. Not intended for any clinical use.
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