IK1 inhibitor PA-6

Cat. No: CDIA-1065

CAS. No.: 500715-03-7

Synonyms: PA-6

Size: 5 mg

Price: Inquiry

Product Details
Formula	C31H32N4O2
Molecular Weight	492.61
Appearance	Solid
Purity	99.62%
Smiles String	N=C(C1=CC=CC=C1)NC2=CC=C(OCCCCCOC3=CC=C(NC(C4=CC=CC=C4)=N)C=C3)C=C2

Storage & Handling
Shipping	Room temperature.
Storage Powder	-20 °C/3 years, 4 °C/2 years

Description

IK1 inhibitor PA-6 (PA-6), a pentamidine analogue, is a selective and potent IK1 (KIR2.x ion-channel-carried inward rectifier current) inhibitor, with IC50 values of 12-15 nM for human and mouse KIR2.x currents. IK1 inhibitor PA-6 (PA-6) elevates KIR2.1 protein expression and induces intracellular KIR2.1 accumulation. IK1 inhibitor PA-6 (PA-6) has the potential to treat atrial fibrillation and arrhythmia.

! For research use only. Not intended for any clinical use.