HS56
Cat. No: CDIA-1856
CAS. No.: 922050-57-5
Size: 50 mg
Product Details |
Formula |
C13H8ClN5OS |
Molecular Weight |
317.75 |
Smiles String |
N#CCSC1=NC(N(C2=CC=CC(Cl)=C2)N=C3)=C3C(N1)=O |
Storage & Handling |
Shipping |
Room temperature. |
Storage |
Please refer to the instruction manual. |
Description
HS56 is an ATP-competitive dual Pim/DAPK3 inhibitor with Ki values of 0.26, 0.208, 2.94, and >100 μM for DAPK3, Pim-3, Pim-1, and Pim-2, respectively. HS56 inhibits LC20 phosphorylation and smooth muscle contraction. HS56 decreases blood pressure in spontaneously hypertensive mice. HS56 can be used in research of hypertension.
! For research use only. Not intended for any clinical use.
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