HET0016
Cat. No: CDIA-0250
CAS. No.: 339068-25-6
Size: 1 mg
Product Details |
Formula |
C12H18N2O |
Molecular Weight |
206.28 |
Appearance |
Solid |
Purity |
99.77% |
Smiles String |
CCCCC1=CC=C(C(C)=C1)/N=C/NO |
Storage & Handling |
Shipping |
Room temperature. |
Storage Powder |
-20 °C/3 years, 4 °C/2 years |
Description
HET0016 is a potent and selective 20-hydroxyeicosatetraenoic acid (20-HETE) synthase inhibitor, with IC50 values of 17.7 nM, 12.1 nM and 20.6 nM for recombinant CYP4A1-, CYP4A2- and CYP4A3-catalyzed 20-HETE synthesis, respectively. HET0016 also is a selective CYP450 inhibitor, which has been shown to inhibit angiogenesis and tumor growth.
! For research use only. Not intended for any clinical use.
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