GW9508
Cat. No: CDIA-0145
CAS. No.: 885101-89-3
Size: 1 mg
Product Details |
Formula |
C22H21NO3 |
Molecular Weight |
347.41 |
Appearance |
Solid |
Purity |
99.33% |
Smiles String |
O=C(O)CCC1=CC=C(NCC2=CC=CC(OC3=CC=CC=C3)=C2)C=C1 |
Storage & Handling |
Shipping |
Room temperature. |
Storage Powder |
-20 °C/3 years, 4 °C/2 years |
Description
GW9508 is a potent and selective G protein-coupled receptors FFA1 (GPR40) and GPR120 agonist with pEC50s of 7.32 and 5.46, respectively. GW9508 shows ~100-fold selectivity for GPR40 over GPR120. GW9508 is inactive against other GPCRs, kinases, proteases, integrins and PPARs. GW9508 is a glucose-sensitive insulin secretagogue and an ATP-sensitive potassium (KATP) channels opener. Anti-inflammatory and anti-atherosclerotic activities.
! For research use only. Not intended for any clinical use.
Related Products