GsMTx4

Cat. No: CDIA-0052

Size: 1 mg

Price: Inquiry

Product Details
Formula	C185H273N49O45S6
Molecular Weight	4095.83
Appearance	Solid
Purity	98.71%
Sequence Shortening	GCLEFWWKCNPNDDKCCRPKLKCSKLFKLCNFSF-NH2 (Disulfide bridge:Cys2-Cys17, Cys9-Cys17, Cys16-Cys30)

Storage & Handling
Shipping	Room temperature.
Storage	Sealed storage, away from moisture and light *In solvent : -80 °C, 6 months; -20 °C, 1 month (sealed storage, away from moisture and light)
Storage Powder	-80 °C/2 years, -20 °C/1 year

Description

GsMTx4 is a spider venom peptide that selectively inhibits cationic-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. GsMTx4 also blocks cation-selective stretch-activated channels (SACs) , attenuates lysophosphatidylcholine (LPC)-induced astrocyte toxicity and microglial reactivity. GsMTx4 is an important pharmacological tool for identifying the role of these excitatory MSCs in normal physiology and pathology.

! For research use only. Not intended for any clinical use.