GSK-114

Cat. No: CDIA-1809

CAS. No.: 1301761-96-5

Size: 50 mg

Price: Inquiry

Product Details
Formula	C19H23N5O4S
Molecular Weight	417.48
Appearance	Solid
Purity	98.08%
Smiles String	O=S(NC)(C1=CC=C(N(C)C)C(NC2=C3C=C(OC)C(OC)=CC3=NC=N2)=C1)=O

Storage & Handling
Shipping	Room temperature.
Storage Powder	-20 °C/3 years, 4 °C/2 years

Description

GSK-114 is a highly selective, orally active TNNI3K inhibitor (IC50= 25 nM). GSK-114 shows a 40-fold selectivity for TNNI3K over B-Raf kinase (IC50= 1 µM). Cardiac troponin I-interacting kinase (TNNI3K or CARK) is a member of the tyrosine-like kinase family that is selectively expressed in heart tissue.

! For research use only. Not intended for any clinical use.