GGsTop
Cat. No: CDIA-0606
CAS. No.: 926281-37-0
Synonyms: Nahlsgen
Size: 5 mg
Product Details |
Formula |
C13H18NO7P |
Molecular Weight |
331.26 |
Appearance |
Solid |
Purity |
99.35% |
Smiles String |
O=C(O)CC1=CC=CC(OP(OC)(CCC(N)C(O)=O)=O)=C1 |
Storage & Handling |
Shipping |
Room temperature. |
Storage Powder |
-20 °C/3 years, 4 °C/2 years |
Description
GGsTop (Nahlsgen) is a potent, non-toxic, highly selective and irreversible γ−glutamyl transpeptidase (GGT) inhibitor, with a Ki of 170 μM for Human GGT. GGsTop shows a pKa of 9.71, also exhibits Kons of 150±10 and 51±3 M-1 s-1 against E.coli GGT and human GGT, respectively. GGsTop protects hepatic ischemia-reperfusion injury in rat model.
! For research use only. Not intended for any clinical use.
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