GATA4-NKX2-5-IN-1
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GATA4-NKX2-5-IN-1

Cat. No: CDIA-1138
CAS. No.: 544681-96-1
Size: 50 mg
Price: Inquiry
Product Details
Formula C21H23N3O2
Molecular Weight 349.43
Appearance Solid
Purity 99.24%
Smiles String CC1=C(C(NC2=CC=C(N(CC)CC)C=C2)=O)C(C3=CC=CC=C3)=NO1
Storage & Handling
Shipping Room temperature.
Storage Powder -20 °C/3 years, 4 °C/2 years

Description

GATA4-NKX2-5-IN-1 (Compound 3) dose-dependently inhibits the GATA4–NKX2-5 transcriptional synergy with an IC50 of 3 μM. GATA4-NKX2-5-IN-1 exhibits no activity on the protein kinases involved in the regulation of GATA4 phosphorylation, and it modulates the hypertrophic agonist-induced cardiac gene expression.

! For research use only. Not intended for any clinical use.