Fasentin
Cat. No: CDIA-0373
CAS. No.: 392721-37-8
Size: 1 mg
Product Details |
Formula |
C11H9ClF3NO2 |
Molecular Weight |
279.64 |
Appearance |
Oil |
Purity |
≥98.0% |
Smiles String |
CC(CC(NC1=CC=C(Cl)C(C(F)(F)F)=C1)=O)=O |
Storage & Handling |
Shipping |
Room temperature. |
Storage Pure Form |
-20 °C/3 years||||4 °C/2 years |
Description
Fasentin, a potent glucose uptake inhibitor, inhibits GLUT-1/GLUT-4 transporters. Fasentin preferentially inhibits GLUT4 (IC50=68 μM) over GLUT1. Fasentin is a death receptor stimuli (FAS) sensitizer and sensitizes cells to FAS-induced cell death. Fasentin is also a tumor necrosis factor (TNF) apoptosis-inducing ligand sensitizer. Fasentin blocks glucose uptake in cancer cell lines and has anti-angiogenic activity.
! For research use only. Not intended for any clinical use.
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