ERK5-IN-2

Cat. No: CDIA-0543

CAS. No.: 1888305-96-1

Size: 1 mg

Price: Inquiry

Product Details
Formula	C17H11BrFN3O2
Molecular Weight	388.19
Appearance	Solid
Purity	98.97%
Smiles String	FC1=CC=CC(Br)=C1C(C2=CNC(C(NC3=CC=CN=C3)=O)=C2)=O

Storage & Handling
Shipping	Room temperature.
Storage	4 °C, protect from light *In solvent : -80 °C, 6 months; -20 °C, 1 month (protect from light)

Description

ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC50s of 0.82 μM, 3 μM for ERK5 and ERK5 MEF2D, respectively. ERK5-IN-2 does not interact with the BRD4 bromodomain. ERK5-IN-2 suppresses both tumor xenograft growth and basic fibroblast growth factor (bFGF) driven Matrigel plug angiogenesis.

! For research use only. Not intended for any clinical use.