ELA-21, (human)

Cat. No: CDIA-1565

CAS. No.: 2245073-05-4

Size: 50 mg

Price: Inquiry

Product Details
Formula	C112H184N40O25S3
Molecular Weight	2587.14
Appearance	Solid
Purity	98.92%
Sequence	Leu-Arg-Lys-His-Asn-Cys-Leu-Gln-Arg-Arg-Cys-Met-Pro-Leu-His-Ser-Arg-Val-Pro-Phe-Pro (Disulfide bridge: Cys6-Cys11)
Sequence Shortening	LRKHNCLQRRCMPLHSRVPFP (Disulfide bridge: Cys6-Cys11)

Storage & Handling
Shipping	Room temperature.
Storage	Sealed storage, away from moisture and light, under nitrogen *In solvent : -80 °C, 6 months; -20 °C, 1 month (sealed storage, away from moisture and light, under nitrogen)
Storage Powder	-80 °C/2 years, -20 °C/1 year

Description

ELA-21 (human) is an apelin receptor agonist with a pKi of 8.52. ELA-21 (human) completely inhibits Forskolin-induced cAMP production and stimulates β-arrestin recruitment with subnanomolar potencies. ELA-21 (human) is an agonist in G-protein-dependent and -independent pathways.

! For research use only. Not intended for any clinical use.