EHNA hydrochloride

Product Details
Formula	C14H24ClN5O
Molecular Weight	313.83
Appearance	Solid
Purity	99.61%
Smiles String	CCCCCC[[email protected]@](N1C2=C(C(N)=NC=N2)N=C1)([H])[[email protected]](O)C.[Relative stereochemistry].Cl

Storage & Handling
Shipping	Room temperature.
Storage	-20 °C, sealed storage, away from moisture *In solvent : -80 °C, 6 months; -20 °C, 1 month (sealed storage, away from moisture)

EHNA hydrochloride is a potent and selective dual inhibitor of cyclic nucleotide phosphodiesterase 2 (PDE2)(IC50=4 μM) and adenosine deaminase (ADA). EHNA hydrochloride exerts a concentration inhibition of the cGMP-stimulated PDE II (cGs-PDE)(IC50:0.8 μM (human), 2 μM (porcine myocardium)), but has smaller inhibitory effect on the unstimulated PDE2 activity. EHNA hydrochloride play roles in mediating diverse pharmacological responses, including antiviral, antitumour and antiarrhythmic effects.

! For research use only. Not intended for any clinical use.