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Dot1l-Flox

Cat. No: CDM0079

Nomenclature: C57BL/6J-Dot1l^em1(flox)

Strain State: Developing

Gene Summary
Human Ortholog	DOT1L
MGI ID	2143886
Gene ID	208266
Target Name	Dot1l
Synonyms	Dot1, KMT4, mDot1, AW907654, A630076O07

Model Description
Description	These mice carry loxP sites flanking target exons of Dot1l gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Dot1l gene.
Disease Connection	Dilated Cardiomyopathy 1A
Phenotype(s)	5424158
Note	The expected phenotype(s) may be observed in the above-mentioned mice that bred with Myhca-cre mice.

! For research use only. Not intended for any clinical use.