Dooku1
Online Inquiry
* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

Dooku1

Cat. No: CDIA-0037
CAS. No.: 2253744-54-4
Size: 1 mg
Price: Inquiry
Product Details
Formula C13H9Cl2N3OS
Molecular Weight 326.20
Appearance Solid
Purity 99.89%
Smiles String ClC1=C(C(Cl)=CC=C1)CSC2=NN=C(C3=CC=CN3)O2
Storage & Handling
Shipping Room temperature.
Storage -20 °C, sealed storage, away from moisture *In solvent : -80 °C, 6 months; -20 °C, 1 month (sealed storage, away from moisture)

Description

Dooku1, an analog of Yoda1, is a selective antagonist of the endogenous Piezo1 channel. Dooku1 inhibited 2 μM Yoda1-induced Ca2+-entry with IC50 values of 1.3 μM (in HEK 293 cells) and 1.5 μM (in HUVECs). Dooku1 inhibits Yoda1-induced relaxation of aorta.

! For research use only. Not intended for any clinical use.