DMX-5804

Cat. No: CDIA-0258

CAS. No.: 2306178-56-1

Size: 1 mg

Price: Inquiry

Product Details
Formula	C21H19N3O3
Molecular Weight	361.39
Appearance	Solid
Purity	99.63%
Smiles String	O=C1NC=NC2=C1C(C3=CC=C(OCCOC)C=C3)=CN2C4=CC=CC=C4

Storage & Handling
Shipping	Room temperature.
Storage Powder	-20 °C/3 years, 4 °C/2 years

Description

DMX-5804 is a potent, orally active and selective MAP4K4 inhibitor, with an IC50 of 3 nM, a pIC50 of 8.55 for human MAP4K4, less potent on MINK1/MAP4K6 (pIC50, 8.18), and TNIK/MAP4K7 (pIC50, 7.96). DMX-5804 enhances cardiomyocyte survival, and reduces ischemia-reperfusion injury in mice.

! For research use only. Not intended for any clinical use.