Deoxyshikonin
Cat. No: CDIA-0590
CAS. No.: 43043-74-9
Size: 5 mg
Product Details |
Formula |
C16H16O4 |
Molecular Weight |
272.30 |
Appearance |
Solid |
Purity |
99.96% |
Smiles String |
O=C1C(CC/C=C(C)/C)=CC(C2=C1C(O)=CC=C2O)=O |
Storage & Handling |
Shipping |
Room temperature. |
Storage |
4 °C, protect from light
*In solvent : -80 °C, 6 months; -20 °C, 1 month (protect from light) |
Description
Deoxyshikonin is isolated from Arnebia euchroma with antitumor activity. Deoxyshikonin increases the expression of VEGF-C and VEGF-A mRNA in HMVEC-dLy, promotes HIF-1α and HIF-1β subunit interaction and binds to specific DNA sequences targeted by HIF, indicates a prolymphangiogenesis as well as a proangiogenesis effect in vitro. Deoxyshikonin shows significant synergic antimicrobial activity against S. pneumonia (MIC=17 μg/mL), also shows significantly inhibitory activities against MRSA.
! For research use only. Not intended for any clinical use.
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